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X-ray Structures of Human Furin in Complex with Competitive Inhibitors

[Image: see text] Furin inhibitors are promising therapeutics for the treatment of cancer and numerous infections caused by bacteria and viruses, including the highly lethal Bacillus anthracis or the pandemic influenza virus. Development and improvement of inhibitors for pharmacological use require...

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Detalhes bibliográficos
Main Authors: Dahms, Sven O., Hardes, Kornelia, Becker, Gero L., Steinmetzer, Torsten, Brandstetter, Hans, Than, Manuel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026159/
https://ncbi.nlm.nih.gov/pubmed/24666235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500087x
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