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Purification of the proprotein convertase furin by affinity chromatography based on PC-specific inhibitors
In eucaryotes, many secreted proteins and peptides are proteolytically excised from larger precursor proteins by a specific class of serine proteases, the proprotein/prohormone convertases (PCs). This cleavage is essential for substrate activation, making the PCs very interesting pharmacological tar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791315/ https://ncbi.nlm.nih.gov/pubmed/21875402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2011.100 |
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