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Double Blockade of CD14 and Complement C5 Abolishes the Cytokine Storm and Improves Morbidity and Survival in Polymicrobial Sepsis in Mice

Sepsis and septic shock, caused by an excessive systemic host-inflammatory response, are associated with high morbidity and mortality. The complement system and TLRs provide important pattern recognition receptors initiating the cytokine storm by extensive cross-talk. We hypothesized that double blo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Huber-Lang, Markus, Barratt-Due, Andreas, Pischke, Søren E., Sandanger, Øystein, Nilsson, Per H., Nunn, Miles A., Denk, Stephanie, Gaus, Wilhelm, Espevik, Terje, Mollnes, Tom E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: AAI 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025614/
https://ncbi.nlm.nih.gov/pubmed/24790148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400341
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