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Human Endothelial Cell Activation by Escherichia coli and Staphylococcus aureus Is Mediated by TNF and IL-1β Secondarily to Activation of C5 and CD14 in Whole Blood

Endothelial cells (EC) play a central role in inflammation. E-selectin and ICAM-1 expression are essential for leukocyte recruitment and are good markers of EC activation. Most studies of EC activation are done in vitro using isolated mediators. The aim of the present study was to examine the relati...

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Publicado en:J Immunol
Autores principales: Nymo, Stig, Gustavsen, Alice, Nilsson, Per H., Lau, Corinna, Espevik, Terje, Mollnes, Tom Eirik
Formato: Artigo
Lenguaje:Inglês
Publicado: AAI 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760234/
https://ncbi.nlm.nih.gov/pubmed/26800874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502220
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