Mitochondrial matrix P53 sensitizes cells to oxidative stress

A mitochondrial matrix-specific p53 construct (termed p53–290) in HepG2 cells was utilized to determine the impact of p53 in the mitochondrial matrix following oxidative stress. H(2)O(2) exposure reduced cellular proliferation similarly in both p53–290 and vector cells, and p53–290 cells demonstrati...

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Hlavní autoři: Koczor, Christopher A., Torres, Rebecca A., Fields, Earl J., Boyd, Amy, Lewis, William
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022151/
https://ncbi.nlm.nih.gov/pubmed/23499753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2013.03.001
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