Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

Mitochondrial Lon is a multi-function matrix protease with chaperone activity. However, little literature has been undertaken into detailed investigations on how Lon regulates apoptosis through its chaperone activity. Accumulating evidences indicate that various stresses induce transportation of p53...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sung, Ya-Ju, Kao, Ting-Yu, Kuo, Cheng-Liang, Fan, Chi-Chen, Cheng, An Ning, Fang, Wei-Cheng, Chou, Han-Yu, Lo, Yu-Kang, Chen, Chung-Hsing, Jiang, Shih Sheng, Chang, I-Shou, Hsu, Chun-Hua, Lee, Jin-Ching, Lee, Alan Yueh-Luen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998145/
https://ncbi.nlm.nih.gov/pubmed/29899330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0730-7
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