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p53 and Mitochondrial DNA: Their Role in Mitochondrial Homeostasis and Toxicity of Antiretrovirals

The roles and actions of the tumor suppressor protein p53 have been extensively studied with regard to nuclear events, including transcription and DNA damage repair. However, the direct roles of p53 in mitochondrial DNA (mtDNA) replication and function are less well understood. Studies herein used a...

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Detalhes bibliográficos
Main Authors: Koczor, Christopher A., White, Richard C., Zhao, Peter, Zhu, Linjue, Fields, Earl, Lewis, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378848/
https://ncbi.nlm.nih.gov/pubmed/22469844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.045
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