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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes
Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...
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| Publicado no: | Physiol Genomics |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/ https://ncbi.nlm.nih.gov/pubmed/26757797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015 |
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