Ecstasy (MDMA) Alters Cardiac Gene Expression and DNA Methylation: Implications for Circadian Rhythm Dysfunction in the Heart

MDMA (ecstasy) is an illicit drug that stimulates monoamine neurotransmitter release and inhibits reuptake. MDMA’s acute cardiotoxicity includes tachycardia and arrhythmia which are associated with cardiomyopathy. MDMA acute cardiotoxicity has been explored, but neither long-term MDMA cardiac pathol...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Koczor, Christopher A., Ludlow, Ivan, Hight, Robert S., Jiao, Zhe, Fields, Earl, Ludaway, Tomika, Russ, Rodney, Torres, Rebecca A., Lewis, William
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
MDMA-Induced DNA Methylation and Gene Expression in the Heart
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731408/
https://ncbi.nlm.nih.gov/pubmed/26251327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv170
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