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Transgenic Mouse Model with Deficient Mitochondrial Polymerase Exhibits Reduced State IV Respiration and Enhanced Cardiac Fibrosis

Mitochondria produce the energy required for proper cardiac contractile function, and cardiomyocytes that exhibit reduced mitochondrial electron transport will have reduced energy production and decreased contractility. Mitochondrial DNA (mtDNA) encodes the core subunits for the protein complexes of...

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書誌詳細
主要な著者: Koczor, Christopher A., Torres, Rebecca A., Fields, Earl, Qin, Qianhong, Park, Jade, Ludaway, Tomika, Russ, Rodney, Lewis, William
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556371/
https://ncbi.nlm.nih.gov/pubmed/23090637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2012.146
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