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Reproductive aging is associated with decreased mitochondrial abundance and altered structure in murine oocytes

PURPOSE: To establish the phenotype of reproductive aging in our mouse model. To test the hypotheses that reproductive aging is associated with a decrease in mitochondrial abundance that could ultimately reflect dysfunction in oocytes. METHODS: Breeding studies were performed in young and aged femal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kushnir, Vitaly A., Ludaway, Tomika, Russ, Rodney B., Fields, Earl J., Koczor, Christopher, Lewis, William
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401248/
https://ncbi.nlm.nih.gov/pubmed/22527902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-012-9771-5
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