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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes

Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...

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Bibliografiska uppgifter
I publikationen:Physiol Genomics
Huvudupphovsmän: Koczor, Christopher A., Ludlow, Ivan, Fields, Earl, Jiao, Zhe, Ludaway, Tomika, Russ, Rodney, Lewis, William
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/
https://ncbi.nlm.nih.gov/pubmed/26757797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015
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