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Mitochondrial matrix P53 sensitizes cells to oxidative stress

A mitochondrial matrix-specific p53 construct (termed p53–290) in HepG2 cells was utilized to determine the impact of p53 in the mitochondrial matrix following oxidative stress. H(2)O(2) exposure reduced cellular proliferation similarly in both p53–290 and vector cells, and p53–290 cells demonstrati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koczor, Christopher A., Torres, Rebecca A., Fields, Earl J., Boyd, Amy, Lewis, William
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022151/
https://ncbi.nlm.nih.gov/pubmed/23499753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2013.03.001
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