Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy

Transgenic mice (TG) were used to define mitochondrial oxidative stress and cardiomyopathy (CM) induced by zidovudine (AZT), an antiretroviral used to treat HIV/AIDS. Genetically engineered mice either depleted or overexpressed mitochondrial superoxide dismutase (SOD2(+/−) KOs and SOD2-OX, respectiv...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Lab Invest
Hoofdauteurs: Kohler, James J, Cucoranu, Ioan, Fields, Earl, Green, Elgin, He, Stanley, Hoying, Amy, Russ, Rodney, Abuin, Allison, Johnson, David, Hosseini, Seyed H, Raper, C Michael, Lewis, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712498/
https://ncbi.nlm.nih.gov/pubmed/19398959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.39
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items