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DNA Damage by Histone Radicals in Nucleosome Core Particles

[Image: see text] Although DNA binding proteins shield the genetic material from diffusible reactive oxygen species by reacting with them, the resulting protein (peroxyl) radicals can oxidize the bound DNA. To explore this possible DNA damage by protein radicals, histone H4 proteins containing an az...

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Detalhes bibliográficos
Main Authors: Zhou, Chuanzheng, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017609/
https://ncbi.nlm.nih.gov/pubmed/24754228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501285s
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