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DNA Damage by Histone Radicals in Nucleosome Core Particles

[Image: see text] Although DNA binding proteins shield the genetic material from diffusible reactive oxygen species by reacting with them, the resulting protein (peroxyl) radicals can oxidize the bound DNA. To explore this possible DNA damage by protein radicals, histone H4 proteins containing an az...

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書目詳細資料
Main Authors: Zhou, Chuanzheng, Greenberg, Marc M.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017609/
https://ncbi.nlm.nih.gov/pubmed/24754228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501285s
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