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Nucleosome core particle catalyzed strand scission at abasic sites()

The reactivity of apurinic/apyrimidinic (AP) sites at different locations within nucleosome core particles was examined. AP sites are greatly destabilized in nucleosome core particles compared to free DNA. Their reactivity varied ~5-fold with respect to location within the nucleosome core particles,...

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Auteurs principaux: Sczepanski, Jonathan T., Zhou, Chuanzheng, Greenberg, Marc M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718853/
https://ncbi.nlm.nih.gov/pubmed/23480734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3010076
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