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Nucleosome core particle catalyzed strand scission at abasic sites()
The reactivity of apurinic/apyrimidinic (AP) sites at different locations within nucleosome core particles was examined. AP sites are greatly destabilized in nucleosome core particles compared to free DNA. Their reactivity varied ~5-fold with respect to location within the nucleosome core particles,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718853/ https://ncbi.nlm.nih.gov/pubmed/23480734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3010076 |
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