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Rotational Effects Within Nucleosome Core Particles on Abasic Site Reactivity

An abasic (AP) site is a ubiquitous DNA lesion that is produced via several cellular processes. Although AP sites are cytotoxic and mutagenic, cells are protected from them by different DNA damage tolerance and repair pathways, including base excision repair (BER). AP lesions are alkali-labile but t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Wang, Ruixiang, Yang, Kun, Banerjee, Samya, Greenberg, Marc M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030455/
https://ncbi.nlm.nih.gov/pubmed/29894168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00493
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