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Rotational Effects Within Nucleosome Core Particles on Abasic Site Reactivity

An abasic (AP) site is a ubiquitous DNA lesion that is produced via several cellular processes. Although AP sites are cytotoxic and mutagenic, cells are protected from them by different DNA damage tolerance and repair pathways, including base excision repair (BER). AP lesions are alkali-labile but t...

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Bibliografiska uppgifter
I publikationen:Biochemistry
Huvudupphovsmän: Wang, Ruixiang, Yang, Kun, Banerjee, Samya, Greenberg, Marc M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030455/
https://ncbi.nlm.nih.gov/pubmed/29894168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00493
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