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Rotational Effects Within Nucleosome Core Particles on Abasic Site Reactivity

An abasic (AP) site is a ubiquitous DNA lesion that is produced via several cellular processes. Although AP sites are cytotoxic and mutagenic, cells are protected from them by different DNA damage tolerance and repair pathways, including base excision repair (BER). AP lesions are alkali-labile but t...

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Bibliografische gegevens
Gepubliceerd in:Biochemistry
Hoofdauteurs: Wang, Ruixiang, Yang, Kun, Banerjee, Samya, Greenberg, Marc M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030455/
https://ncbi.nlm.nih.gov/pubmed/29894168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00493
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