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Rotational Effects Within Nucleosome Core Particles on Abasic Site Reactivity
An abasic (AP) site is a ubiquitous DNA lesion that is produced via several cellular processes. Although AP sites are cytotoxic and mutagenic, cells are protected from them by different DNA damage tolerance and repair pathways, including base excision repair (BER). AP lesions are alkali-labile but t...
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| Опубликовано в: : | Biochemistry |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030455/ https://ncbi.nlm.nih.gov/pubmed/29894168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00493 |
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