E prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection

Prostaglandins (PGs) are potent lipid mediators that are produced during infections and whose synthesis and signaling networks present potential pharmacologic targets for immunomodulation. PGE(2) acts through the ligation of 4 distinct G protein coupled receptors, E-prostanoid (EP) 1–4. Previous in...

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Detaylı Bibliyografya
Asıl Yazarlar: Aronoff, David M., Lewis, Casey, Serezani, Carlos H., Eaton, Kathryn A., Goel, Deepti, Phipps, John J., Peters-Golden, Marc, Mancuso, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016992/
https://ncbi.nlm.nih.gov/pubmed/19635910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900129
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