E Prostanoid 2 Receptor Signaling Suppresses Lung Innate Immunity against Streptococcus pneumoniae

Pneumonia is a major global health problem. Prostaglandin (PG) E(2) is an immunomodulatory lipid with anti-inflammatory, immunosuppressive, and pro-resolving actions. Data suggest that the E-prostanoid (EP) 2 receptor mediates immunomodulatory effects of PGE(2), but the extent to which this occurs i...

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Autores principales: Aronoff, David M., Bergin, Ingrid L., Lewis, Casey, Goel, Deepti, O’Brien, Edmund, Peters-Golden, Marc, Mancuso, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350638/
https://ncbi.nlm.nih.gov/pubmed/22575745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2012.03.002
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