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E prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection
Prostaglandins (PGs) are potent lipid mediators that are produced during infections and whose synthesis and signaling networks present potential pharmacologic targets for immunomodulation. PGE(2) acts through the ligation of 4 distinct G protein coupled receptors, E-prostanoid (EP) 1–4. Previous in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016992/ https://ncbi.nlm.nih.gov/pubmed/19635910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900129 |
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