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E prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection
Prostaglandins (PGs) are potent lipid mediators that are produced during infections and whose synthesis and signaling networks present potential pharmacologic targets for immunomodulation. PGE(2) acts through the ligation of 4 distinct G protein coupled receptors, E-prostanoid (EP) 1–4. Previous in...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016992/ https://ncbi.nlm.nih.gov/pubmed/19635910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900129 |
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