E prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection

Prostaglandins (PGs) are potent lipid mediators that are produced during infections and whose synthesis and signaling networks present potential pharmacologic targets for immunomodulation. PGE(2) acts through the ligation of 4 distinct G protein coupled receptors, E-prostanoid (EP) 1–4. Previous in...

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Bibliografiset tiedot
Päätekijät: Aronoff, David M., Lewis, Casey, Serezani, Carlos H., Eaton, Kathryn A., Goel, Deepti, Phipps, John J., Peters-Golden, Marc, Mancuso, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016992/
https://ncbi.nlm.nih.gov/pubmed/19635910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900129
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