The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation

The Drosophila protein brain tumor (Brat) forms a complex with Pumilio (Pum) and Nanos (Nos) to repress hunchback (hb) mRNA translation at the posterior pole during early embryonic development. It is currently thought that complex formation is initiated by Pum, which directly binds the hb mRNA and s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Loedige, Inga, Stotz, Mathias, Qamar, Saadia, Kramer, Katharina, Hennig, Janosch, Schubert, Thomas, Löffler, Patrick, Längst, Gernot, Merkl, Rainer, Urlaub, Henning, Meister, Gunter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015489/
https://ncbi.nlm.nih.gov/pubmed/24696456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.236513.113
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