Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition

RNA-binding proteins regulate all aspects of RNA metabolism. Their association with RNA is mediated by RNA-binding domains, of which many remain uncharacterized. A recently reported example is the NHL domain, found in prominent regulators of cellular plasticity like the C. elegans LIN-41. Here we em...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kumari, Pooja, Aeschimann, Florian, Gaidatzis, Dimos, Keusch, Jeremy J., Ghosh, Pritha, Neagu, Anca, Pachulska-Wieczorek, Katarzyna, Bujnicki, Janusz M., Gut, Heinz, Großhans, Helge, Ciosk, Rafal
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908797/
https://ncbi.nlm.nih.gov/pubmed/29674686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03920-7
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