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The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda

The TRIM‐NHL protein Brain tumor (Brat) acts as a tumor suppressor in the Drosophila brain, but how it suppresses tumor formation is not completely understood. Here, we combine temperature‐controlled brat RNAi with transcriptome analysis to identify the immediate Brat targets in Drosophila neuroblas...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Reichardt, Ilka, Bonnay, François, Steinmann, Victoria, Loedige, Inga, Burkard, Thomas R, Meister, Gunter, Knoblich, Juergen A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757284/
https://ncbi.nlm.nih.gov/pubmed/29191977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744188
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