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The Tumor Suppressors Brat and Numb Regulate Transit-Amplifying Neuroblast Lineages in Drosophila

In both vertebrates and insects, neurons typically arise from neural stem cells or terminally dividing intermediate progenitors. Here, we describe another mode of neurogenesis where neural stem cells generate secondary precursors that undergo multiple rounds of self-renewing transit-amplifying divis...

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Autors principals: Bowman, Sarah K., Rolland, Vivien, Betschinger, Joerg, Kinsey, Kaolin A., Emery, Gregory, Knoblich, Juergen A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988195/
https://ncbi.nlm.nih.gov/pubmed/18342578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.004
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