The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation

The Drosophila protein brain tumor (Brat) forms a complex with Pumilio (Pum) and Nanos (Nos) to repress hunchback (hb) mRNA translation at the posterior pole during early embryonic development. It is currently thought that complex formation is initiated by Pum, which directly binds the hb mRNA and s...

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Detaylı Bibliyografya
Asıl Yazarlar: Loedige, Inga, Stotz, Mathias, Qamar, Saadia, Kramer, Katharina, Hennig, Janosch, Schubert, Thomas, Löffler, Patrick, Längst, Gernot, Merkl, Rainer, Urlaub, Henning, Meister, Gunter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2014
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015489/
https://ncbi.nlm.nih.gov/pubmed/24696456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.236513.113
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