Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer

BACKGROUND: Ranpirnase (Rap) is an amphibian ribonuclease with reported antitumor activity, minimal toxicity, and negligible immunogenicity in clinical studies, but the unfavorable pharmacokinetics and suboptimal efficacy hampered its further clinical development. To improve the potential of Rap-bas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Liu, Donglin, Cardillo, Thomas M, Wang, Yang, Rossi, Edmund A, Goldenberg, David M, Chang, Chien-Hsing
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015355/
https://ncbi.nlm.nih.gov/pubmed/24606732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-53
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares