Llwytho...

Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer

BACKGROUND: Ranpirnase (Rap) is an amphibian ribonuclease with reported antitumor activity, minimal toxicity, and negligible immunogenicity in clinical studies, but the unfavorable pharmacokinetics and suboptimal efficacy hampered its further clinical development. To improve the potential of Rap-bas...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Donglin, Cardillo, Thomas M, Wang, Yang, Rossi, Edmund A, Goldenberg, David M, Chang, Chien-Hsing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015355/
https://ncbi.nlm.nih.gov/pubmed/24606732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-53
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