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Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer
BACKGROUND: Ranpirnase (Rap) is an amphibian ribonuclease with reported antitumor activity, minimal toxicity, and negligible immunogenicity in clinical studies, but the unfavorable pharmacokinetics and suboptimal efficacy hampered its further clinical development. To improve the potential of Rap-bas...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015355/ https://ncbi.nlm.nih.gov/pubmed/24606732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-53 |
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