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Structure and Inhibition of Mouse Leukotriene C(4) Synthase
Leukotriene (LT) C(4) synthase (LTC4S) is an integral membrane protein that catalyzes the conjugation reaction between the fatty acid LTA(4) and GSH to form the pro-inflammatory LTC(4), an important mediator of asthma. Mouse models of inflammatory disorders such as asthma are key to improve our unde...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014545/ https://ncbi.nlm.nih.gov/pubmed/24810165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096763 |
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