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The structure of Enterococcus Faecium l,d–transpeptidase acylated by ertapenem provides insight into the inactivation mechanism

The maintenance of bacterial cell shape and integrity is largely attributed to peptidoglycan, a biopolymer highly cross-linked through d,d–transpeptidation. Peptidoglycan cross-linking is catalyzed by Penicillin-Binding Proteins (PBPs) that are the essential target of β-lactam antibiotics. PBPs are...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lecoq, Lauriane, Dubée, Vincent, Triboulet, Sébastien, Bougault, Catherine, Hugonnet, Jean-Emmanuel, Arthur, Michel, Simorre, Jean-Pierre
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013547/
https://ncbi.nlm.nih.gov/pubmed/23574509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4001603
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