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Acyl acceptor recognition by Enterococcus faecium l,d-transpeptidase Ldt(fm)
In Mycobacterium tuberculosis and ampicillin-resistant mutants of Enterococcus faecium, the classical target of β-lactam antibiotics is bypassed by l,d-transpeptidases that form unusual 3→3 peptidoglycan cross-links. β-lactams of the carbapenem class, such as ertapenem, are mimics of the acyl donor...
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| Publicado no: | Mol Microbiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691707/ https://ncbi.nlm.nih.gov/pubmed/26101813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13104 |
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