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Inactivation of Mycobacterium tuberculosis l,d-Transpeptidase Ldt(Mt1) by Carbapenems and Cephalosporins
The structure of Mycobacterium tuberculosis peptidoglycan is atypical since it contains a majority of 3→3 cross-links synthesized by l,d-transpeptidases that replace 4→3 cross-links formed by the d,d-transpeptidase activity of classical penicillin-binding proteins. Carbapenems inactivate these l,d-t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421625/ https://ncbi.nlm.nih.gov/pubmed/22615283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00665-12 |
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