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Kinetic Features of L,D-Transpeptidase Inactivation Critical for β-Lactam Antibacterial Activity
Active-site serine D,D-transpeptidases belonging to the penicillin-binding protein family (PBPs) have been considered for a long time as essential for peptidoglycan cross-linking in all bacteria. However, bypass of the PBPs by an L,D-transpeptidase (Ldt(fm)) conveys high-level resistance to β-lactam...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701632/ https://ncbi.nlm.nih.gov/pubmed/23861815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067831 |
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