Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is sustained by small populations of leukemia stem cells (LSCs) that can resist available treatments and represent important barriers to cure. Although previous studies have shown increased signal transducer and activator of transcription (STAT)3 and STAT5 phosphorylatio...

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Autors principals: Cook, Amy M., Li, Liang, Ho, Yinwei, Lin, Allen, Li, Ling, Stein, Anthony, Forman, Stephen, Perrotti, Danilo, Jove, Richard, Bhatia, Ravi
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007609/
https://ncbi.nlm.nih.gov/pubmed/24668492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-505735
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