Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is sustained by small populations of leukemia stem cells (LSCs) that can resist available treatments and represent important barriers to cure. Although previous studies have shown increased signal transducer and activator of transcription (STAT)3 and STAT5 phosphorylatio...

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Detalhes bibliográficos
Main Authors: Cook, Amy M., Li, Liang, Ho, Yinwei, Lin, Allen, Li, Ling, Stein, Anthony, Forman, Stephen, Perrotti, Danilo, Jove, Richard, Bhatia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007609/
https://ncbi.nlm.nih.gov/pubmed/24668492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-505735
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