Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro

Acute myeloid leukemia (AML) is characterized by a high relapse rate and dismal long-term overall survival which is related to persistence of leukemia-initiating cells in their niche. Different animal models of myeloid malignancies reveal how neoplastic cells alter the structural and functional char...

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Pubblicato in:Blood Adv
Autori principali: Habbel, Jan, Arnold, Lucas, Chen, Yiyang, Möllmann, Michael, Bruderek, Kirsten, Brandau, Sven, Dührsen, Ulrich, Hanoun, Maher
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362361/
https://ncbi.nlm.nih.gov/pubmed/32614965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001292
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