ロード中...
A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA
[Image: see text] Slow-onset enzyme inhibitors are of great interest for drug discovery programs since the slow dissociation of the inhibitor from the drug–target complex results in sustained target occupancy leading to improved pharmacodynamics. However, the structural basis for slow-onset inhibiti...
保存先:
| 主要な著者: | , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical
Society
2014
|
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004265/ https://ncbi.nlm.nih.gov/pubmed/24527857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400896g |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|