Targeting InhA, the FASII Enoyl-ACP Reductase: SAR Studies on Novel Inhibitor Scaffolds

Eitemau Tebyg

• Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase
  gan: Wang, Hui, et al.
  Cyhoeddwyd: (2015)
• In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA)
  gan: Pinzi, Luca, et al.
  Cyhoeddwyd: (2019)
• A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA
  gan: Li, Huei-Jiun, et al.
  Cyhoeddwyd: (2014)
• A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis
  gan: Luckner, Sylvia R., et al.
  Cyhoeddwyd: (2010)
• The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: Adduct affinity and drug resistance
  gan: Rawat, Richa, et al.
  Cyhoeddwyd: (2003)