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Nitric Oxide-Induced Conformational Changes in Soluble Guanylate Cyclase
Soluble guanylate cyclase (sGC) is the primary mediator of nitric oxide (NO) signaling. NO binds the sGC heme cofactor stimulating synthesis of the second messenger cyclic-GMP (cGMP). As the central hub of NO/cGMP signaling pathways, sGC is important in diverse physiological processes such as vasodi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001857/ https://ncbi.nlm.nih.gov/pubmed/24560804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.01.008 |
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