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Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase
Nitric oxide (NO) signaling pathways mediate diverse physiological functions, including vasodilation and neurotransmission. Soluble guanylate cyclase (sGC), the primary NO receptor, triggers downstream signaling cascades by producing the second messenger cGMP. NO binds the sGC heme cofactor to stimu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637750/ https://ncbi.nlm.nih.gov/pubmed/23572573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301934110 |
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