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Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase

Soluble guanylate cyclase (sGC) is the primary nitric oxide (NO) receptor in mammals and a central component of the NO-signaling pathway. The NO-signaling pathways mediate diverse physiological processes, including vasodilation, neurotransmission, and myocardial functions. sGC is a heterodimer assem...

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Hlavní autoři: Campbell, Melody G., Underbakke, Eric S., Potter, Clinton S., Carragher, Bridget, Marletta, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939929/
https://ncbi.nlm.nih.gov/pubmed/24516165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400711111
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