Probing Domain Interactions in Soluble Guanylate Cyclase

Eukaryotic nitric oxide (NO) signaling involves modulation in cyclic GMP (cGMP) levels through activation of the soluble isoform of guanylate cyclase (sGC). sGC is a heterodimeric hemoprotein that contains a Heme-Nitric oxide and OXygen binding (H-NOX) domain, a Per/ARNT/Sim (PAS) domain, a coiled-c...

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Autores principales: Derbyshire, Emily R., Winter, Michael B., Ibrahim, Mohammed, Deng, Sarah, Spiro, Thomas G., Marletta, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096724/
https://ncbi.nlm.nih.gov/pubmed/21491957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200341b
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