Probing Domain Interactions in Soluble Guanylate Cyclase

Eukaryotic nitric oxide (NO) signaling involves modulation in cyclic GMP (cGMP) levels through activation of the soluble isoform of guanylate cyclase (sGC). sGC is a heterodimeric hemoprotein that contains a Heme-Nitric oxide and OXygen binding (H-NOX) domain, a Per/ARNT/Sim (PAS) domain, a coiled-c...

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Main Authors: Derbyshire, Emily R., Winter, Michael B., Ibrahim, Mohammed, Deng, Sarah, Spiro, Thomas G., Marletta, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096724/
https://ncbi.nlm.nih.gov/pubmed/21491957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200341b
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