Probing Domain Interactions in Soluble Guanylate Cyclase

Eukaryotic nitric oxide (NO) signaling involves modulation in cyclic GMP (cGMP) levels through activation of the soluble isoform of guanylate cyclase (sGC). sGC is a heterodimeric hemoprotein that contains a Heme-Nitric oxide and OXygen binding (H-NOX) domain, a Per/ARNT/Sim (PAS) domain, a coiled-c...

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Bibliographic Details
Main Authors: Derbyshire, Emily R., Winter, Michael B., Ibrahim, Mohammed, Deng, Sarah, Spiro, Thomas G., Marletta, Michael A.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096724/
https://ncbi.nlm.nih.gov/pubmed/21491957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200341b
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