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A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase

Nitric oxide (NO) regulates a number of essential physiological processes by activating soluble guanylate cyclase (sGC) to produce the second messenger cGMP. The mechanism of NO sensing was previously thought to result exclusively from NO binding to the sGC heme; however, recent studies indicate tha...

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Detalhes bibliográficos
Main Authors: Fernhoff, Nathaniel B., Derbyshire, Emily R., Marletta, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791033/
https://ncbi.nlm.nih.gov/pubmed/20007374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911083106
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