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The Influence of Nitric Oxide on Soluble Guanylate Cyclase Regulation by Nucleotides: ROLE OF THE PSEUDOSYMMETRIC SITE

Activation of soluble guanylate cyclase (sGC) by the signaling molecule nitric oxide (NO) leads to formation of the second messenger cGMP, which mediates numerous physiological processes. NO activates sGC by binding to the ferrous heme cofactor; the relative amount of NO with respect to sGC heme aff...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sürmeli, Nur Başak, Müskens, Frederike M., Marletta, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505470/
https://ncbi.nlm.nih.gov/pubmed/25907555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641431
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