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Optical Mapping of Sarcoplasmic Reticulum Ca(2+) in the Intact Heart: Ryanodine Receptor Refractoriness During Alternans and Fibrillation
RATIONALE: Sarcoplasmic reticulum (SR) Ca(2+) cycling is key to normal excitation-contraction coupling but may also contribute to pathological cardiac alternans and arrhythmia. OBJECTIVE: To measure intra-SR free [Ca(2+)] ([Ca(2+)](SR)) changes in intact hearts during alternans and ventricular fibri...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000583/ https://ncbi.nlm.nih.gov/pubmed/24568740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302505 |
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