Decreased inward rectifying K(+) current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart

Heart failure (HF) results in dramatic electrophysiological remodelling, including increased sensitivity of ryanodine receptors (RyRs) and decreased inward rectifying K(+) current (I(K1)), which predisposes HF myocytes to delayed afterdepolarizations and triggered activity. Therefore, we sought to d...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Myles, Rachel C, Wang, Lianguo, Bers, Donald M, Ripplinger, Crystal M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376425/
https://ncbi.nlm.nih.gov/pubmed/25772297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.279638
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller